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Save the Vig - Biggest Upsets as of Week 17
A look at 2020's Biggest Upsets.

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(Sep 26)    The Kansas State Wildcats beat the Oklahoma Sooners in their own house as a 28 point underdog.
(Nov 7)    The Maryland Terrapins beat the Penn State Nittany Lions in their own house as a 27 point underdog.
(Oct 31)    The Michigan State Spartans beat the Michigan Wolverines in their own house as a 25 point underdog.
(Dec 5)    The Rice Owls beat the Marshall Thundering Herd in their own house as a 24.5 point underdog.
(Dec 12)    The LSU Tigers beat the Florida Gators in their own house as a 23 point underdog.
(Oct 3)    The Tulsa Golden Hurricane beat the UCF Knights in their own house as a 19.5 point underdog.
(Dec 5)    The New Mexico Lobos beat the Wyoming Cowboys as a 18.0 point home underdog.
(Oct 30)    The Maryland Terrapins beat the Minnesota Golden Gophers as a 17.5 point home underdog.
(Nov 21)    The Illinois Fighting Illini beat the Nebraska Cornhuskers in their own house as a 17 point underdog.
(Oct 3)    The Arkansas Razorbacks beat the Mississippi State Bulldogs in their own house as a 16.5 point underdog.
(Nov 7)    The Liberty Flames beat the Virginia Tech Hokies in their own house as a 16.5 point underdog.
(Sep 19)    The Liberty Flames beat the Western Kentucky Hilltoppers in their own house as a 15.5 point underdog.
(Sep 12)    The Arkansas State Red Wolves beat the Kansas State Wildcats in their own house as a 15.5 point underdog.
(Dec 12)    The New Mexico Lobos beat the Fresno State Bulldogs as a 15.0 point home underdog.
(Sep 26)    The Mississippi State Bulldogs beat the LSU Tigers in their own house as a 14.5 point underdog.
(Oct 10)    The Missouri Tigers beat the LSU Tigers in their own house as a 14 point underdog.
(Oct 3)    The NC State Wolfpack beat the Pittsburgh Panthers in their own house as a 14 point underdog.
(Dec 5)    The Eastern Michigan Eagles beat the Western Michigan Broncos in their own house as a 13.5 point underdog.
(Nov 28)    The Michigan State Spartans beat the Northwestern Wildcats as a 13.5 point home underdog.
(Sep 12)    The Georgia Tech Yellow Jackets beat the Florida State Seminoles in their own house as a 13.5 point underdog.
(Oct 17)    The Florida State Seminoles beat the North Carolina Tar Heels as a 13.5 point home underdog.
(Nov 27)    The Oregon State Beavers beat the Oregon Ducks as a 13.0 point home underdog.
(Sep 3)    The South Alabama Jaguars beat the Southern Mississippi Golden Eagles in their own house as a 12.5 point underdog.
(Dec 5)    The Indiana Hoosiers beat the Wisconsin Badgers in their own house as a 12.5 point underdog.
(Nov 28)    The Rutgers Scarlet Knights beat the Purdue Boilermakers in their own house as a 12 point underdog.
(Nov 28)    The East Carolina Pirates beat the SMU Mustangs as a 12.0 point home underdog.
(Dec 5)    The Stanford Cardinal beat the Washington Huskies in their own house as a 12 point underdog.
(Nov 21)    The Middle Tennessee Blue Raiders beat the Troy Trojans in their own house as a 11.5 point underdog.
(Sep 12)    The Louisiana Ragin' Cajuns beat the Iowa State Cyclones in their own house as a 11 point underdog.
(Oct 3)    The TCU Horned Frogs beat the Texas Longhorns in their own house as a 10.5 point underdog.
(Oct 10)    The Kansas State Wildcats beat the TCU Horned Frogs in their own house as a 10.5 point underdog.
(Oct 24)    The Wake Forest Demon Deacons beat the Virginia Tech Hokies as a 10.5 point home underdog.
(Oct 23)    The Jacksonville State Gamecocks beat the Florida International Golden Panthers in their own house as a 10.5 point underdog.
(Dec 5)    The Coastal Carolina Chanticleers beat the BYU Cougars as a 10.0 point home underdog.
(Oct 31)    The Louisiana Tech Bulldogs beat the UAB Blazers as a 10.0 point home underdog.
(Nov 6)    The San José State Spartans beat the San Diego State Aztecs in their own house as a 10 point underdog.

There have been 36 upsets by teams that were 10 point underdogs or more in the 2020 regular season.
Out of 293 games with spreads of 10 or higher, 36 teams, or 12.29% were able to pull off the outright victory.