(Oct 16) The Louisiana Monroe Warhawks beat the Liberty Flames as a 32.5 point home underdog.
(Nov 13) The Kansas Jayhawks beat the Texas Longhorns in their own house as a 31 point underdog.
(Sep 25) The Bowling Green Falcons beat the Minnesota Golden Gophers in their own house as a 30.5 point underdog.
(Sep 11) The Duquesne Dukes beat the Ohio Bobcats in their own house as a 28.5 point underdog.
(Sep 11) The Jacksonville State Gamecocks beat the Florida State Seminoles in their own house as a 27.5 point underdog.
(Sep 18) The Northern Arizona Lumberjacks beat the Arizona Wildcats in their own house as a 26.5 point underdog.
(Oct 23) The Illinois Fighting Illini beat the Penn State Nittany Lions in their own house as a 24.5 point underdog.
(Sep 25) The Louisiana Monroe Warhawks beat the Troy Trojans as a 23.5 point home underdog.
(Oct 23) The Rice Owls beat the UAB Blazers in their own house as a 23.5 point underdog.
(Sep 4) The Montana Grizzlies beat the Washington Huskies in their own house as a 22.5 point underdog.
(Sep 2) The UC Davis Aggies beat the Tulsa Golden Hurricane in their own house as a 22 point underdog.
(Sep 4) The East Tennessee State Buccaneers beat the Vanderbilt Commodores in their own house as a 21 point underdog.
(Nov 6) The South Carolina Gamecocks beat the Florida Gators as a 20.5 point home underdog.
(Oct 23) The New Mexico Lobos beat the Wyoming Cowboys in their own house as a 20 point underdog.
(Sep 4) The Northern Illinois Huskies beat the Georgia Tech Yellow Jackets in their own house as a 19 point underdog.
(Oct 9) The Texas A&M Aggies beat the Alabama Crimson Tide as a 18.5 point home underdog.
(Oct 9) The Florida State Seminoles beat the North Carolina Tar Heels in their own house as a 17.5 point underdog.
(Sep 4) The Utah State Aggies beat the Washington State Cougars in their own house as a 17.5 point underdog.
(Sep 11) The Stanford Cardinal beat the USC Trojans in their own house as a 17 point underdog.
(Oct 30) The Washington State Cougars beat the Arizona State Sun Devils in their own house as a 16.5 point underdog.
(Oct 2) The Navy Midshipmen beat the UCF Knights as a 15.0 point home underdog.
(Nov 19) The Southern Mississippi Golden Eagles beat the Louisiana Tech Bulldogs in their own house as a 15 point underdog.
(Sep 18) The Colorado State Rams beat the Toledo Rockets in their own house as a 14.5 point underdog.
(Nov 6) The Illinois Fighting Illini beat the Minnesota Golden Gophers in their own house as a 14.5 point underdog.
(Sep 11) The Oregon Ducks beat the Ohio State Buckeyes in their own house as a 14.5 point underdog.
(Sep 18) The Western Michigan Broncos beat the Pittsburgh Panthers in their own house as a 14 point underdog.
(Oct 9) The Akron Zips beat the Bowling Green Falcons in their own house as a 14 point underdog.
(Oct 30) The Bowling Green Falcons beat the Buffalo Bulls in their own house as a 13.5 point underdog.
(Oct 23) The Louisiana Monroe Warhawks beat the South Alabama Jaguars as a 13.5 point home underdog.
(Nov 13) The Texas Tech Red Raiders beat the Iowa State Cyclones as a 13.0 point home underdog.
(Oct 9) The Ball State Cardinals beat the Western Michigan Broncos in their own house as a 13 point underdog.
(Oct 9) The Northern Illinois Huskies beat the Toledo Rockets in their own house as a 13 point underdog.
(Oct 16) The LSU Tigers beat the Florida Gators as a 12.5 point home underdog.
(Nov 13) The Georgia State Panthers beat the Coastal Carolina Chanticleers in their own house as a 12.5 point underdog.
(Nov 6) The Colorado Buffaloes beat the Oregon State Beavers as a 11.5 point home underdog.
(Oct 2) The Temple Owls beat the Memphis Tigers as a 11.0 point home underdog.
(Oct 29) The Navy Midshipmen beat the Tulsa Golden Hurricane in their own house as a 11 point underdog.
(Sep 18) The East Carolina Pirates beat the Marshall Thundering Herd in their own house as a 11 point underdog.
(Sep 18) The Fresno State Bulldogs beat the UCLA Bruins in their own house as a 11 point underdog.
(Sep 25) The Oregon State Beavers beat the USC Trojans in their own house as a 11 point underdog.
(Oct 2) The Middle Tennessee Blue Raiders beat the Marshall Thundering Herd as a 11.0 point home underdog.
(Oct 16) The Purdue Boilermakers beat the Iowa Hawkeyes in their own house as a 11 point underdog.
(Sep 25) The NC State Wolfpack beat the Clemson Tigers as a 10.5 point home underdog.
(Oct 2) The Ball State Cardinals beat the Army Black Knights as a 10.5 point home underdog.
(Sep 18) The Incarnate Word Cardinals beat the Texas State Bobcats in their own house as a 10.5 point underdog.
(Oct 2) The Hawai'i Rainbow Warriors beat the Fresno State Bulldogs as a 10.5 point home underdog.
Out of 443 games with spreads of 10 or higher, 46 teams, or 10.38% were able to pull off the outright victory.